- CAY 10465
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- $30.00 / 1mg
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2024-11-19
- CAS:688348-33-6
- Min. Order:
- Purity: 100%
- Supply Ability: 10g
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| 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Basic information |
Product Name: | 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE | Synonyms: | CAY10465;1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE;1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene;CAY10465 Exclusive;CAY10465;CAY-10465;CAY 10465;CAY-10465,AhR,CAY 10465,inhibit,Inhibitor,Aryl Hydrocarbon Receptor;Benzene, 1,3-dichloro-5-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-;1,3-Dichloro-5-(4-(trifluoromethyl)styryl)benzene | CAS: | 688348-33-6 | MF: | C15H9Cl2F3 | MW: | 317.13 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Chemical Properties |
Boiling point | 361.2±42.0 °C(Predicted) | density | 1.378±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 20 mg/ml | form | A crystalline solid | color | White to off-white |
| 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Usage And Synthesis |
Description | The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. CAY10465 is an analog of resveratrol acting as a potent and selective AhR agonist, with a Ki of 0.2 nM. CAY10465 is inactive as a ligand for the estrogen receptor even at 100 μM. | Uses | (E)-1-[4-(Trifluoromethyl)phenyl]-2-(3,5-dichlorophenyl)ethene is a stilbene derivative of resveratrol and a selective aryl hydrocarbon receptor agonist. |
| 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE Preparation Products And Raw materials |
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