| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-ADARB1
Purity:Prestige Antibodies P Package:100μL Remarks:HPA018277
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Product Name:Monoclonal Anti-ADAR2 antibody produced in mouse
Purity:IgG fraction of antiserum, lyophilized powder Remarks:clone ADAR2-15, IgG fraction of tissue culture supernatant
|
|
| | ANTI-RED-1 Basic information |
| Product Name: | ANTI-RED-1 | | Synonyms: | Anti-ADARB1;Anti-Adenosine Deaminase, RNA-specific B1;Anti-RNA Editase 1;Monoclonal Anti-ADAR2 antibody produced in mouse;Anti-Double-stranded RNA-specific editase 1;Anti-dsRNA adenosine deaminase;Anti-RNA-editing deaminase 1;ANTI-SCAVENGER RECEPTOR BI AND BII | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-RED-1 Structure]() |
| | ANTI-RED-1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-RED-1 Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | The gene ADARB1 (double-stranded RNA-specific editase-1) is mapped to human chromosome 21q22.3. ADARB1 belongs to ADAR gene family, including two other members - ADAR1 and ADAR3. The protein is highly expressed in brain and heart; lower levels are seen in placenta, pancreas and skeletal muscle. Very small amounts are also present in lung, liver and kidney. | | Biochem/physiol Actions | ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. |
| | ANTI-RED-1 Preparation Products And Raw materials |
|