| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Early Endosomal Antigen 1 (N-terminal)
Purity:~ 1mg/mL, affinity isolated antibody, buffered aqueous solut Package:25μL, 200μL Remarks:E4156
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:affinity isolated antibody, lyophilized powder Remarks:clone 1D4, purified immunoglobulin, buffered aqueous solution
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| Company Name: |
BD Biosciences
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| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
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| Products Intro: |
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| Company Name: |
Alexis Corporation
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| Tel: |
+41 61 926 8989 |
| Email: |
alexis-ch@alexis-corp.ch |
| Products Intro: |
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| | ANTI-EEA1 Basic information |
| Product Name: | ANTI-EEA1 | | Synonyms: | ANTI-ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 2;ANTI-EEA1;ANTI-EARLY ENDOSOMAL ANTIGEN 1;ANTI-EARLY ENDOSOMAL ANTIGEN 1 (C-TERMINAL);ANTI-EARLY ENDOSOMAL ANTIGEN 1 (N-TERMINAL);ANTI-ENDOSOME-ASSOCIATED PROTEIN P162;Anti-EEA1 antibody produced in chicken;Anti-early endosome antigen 1, 162kD | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-EEA1 Structure]() |
| | ANTI-EEA1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-EEA1 Usage And Synthesis |
| Uses | Anti-EEA1 antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. | | General Description | The gene Early Endosome Antigen 1 (EEA1) encodes for around 1400 amino acid protein. It is a peripheral membrane protein associated with the cytoplasmic face of early endosomes. EEA1 is a autoantigen associated with subacute cutaneous systemic lupus erythematosus and is a coiled-coil protein localized to early endosomes and cytosol. | | Biochem/physiol Actions | Early Endosome Antigen 1 (EEA1) controls vesicle fusion during endocytosis. In neurons, it is involved in recycling of synaptic vesicles and neurotransmitter receptors. Patients with neurological deficits develop EEA1 autoantibodies. Mutation in EEA1 gene leads to susceptibility to diabetes in the Japanese population. Phosphatidylinositol 3-phosphate (PtdIns(3)P) is essential for the localization and function of EEA1. |
| | ANTI-EEA1 Preparation Products And Raw materials |
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