Everolimus Hydrolized Impurity

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Products Intro: Product Name:769905-89-7
CAS:769905-89-7
Purity:98% HPLC Package:5mg,10mg,50mg,100mg,1g,5g
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Products Intro: Product Name:Everolimus Hydrolized Impurity
CAS:769905-89-7
Purity:>95%
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Products Intro: Product Name:seco Everolimus B
CAS:769905-89-7
Purity:>99% Package:100mg
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Products Intro: Product Name:everolimus
CAS:769905-89-7
Purity:95% HPLC Package:50mg 100mg
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Products Intro: Product Name:seco Everolimus B
CAS:769905-89-7
Purity:NULL Package:5mg Remarks:NULL
Everolimus Hydrolized Impurity Basic information
Product Name:Everolimus Hydrolized Impurity
Synonyms:Everolimus Open-Ring Acid Impurity;seco Everolimus B (~90%);Everolimus Impurity 37;2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoac...
CAS:769905-89-7
MF:C53H85NO15
MW:976.26
EINECS:
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Mol File:769905-89-7.mol
Everolimus Hydrolized Impurity Structure
Everolimus Hydrolized Impurity Chemical Properties
Melting point >110°C (dec.)
Boiling point 1010.0±75.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka3.24±0.20(Predicted)
color Light Beige to Brown
Safety Information
MSDS Information
Everolimus Hydrolized Impurity Usage And Synthesis
Usesseco Everolimus B is a metabolite of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.
Everolimus Hydrolized Impurity Preparation Products And Raw materials
Tag:Everolimus Hydrolized Impurity(769905-89-7) Related Product Information
Everolimus 2-Piperidinecarboxylic acid, 1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-heptenyl es... 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Everolimus EP Impurity E USDOYNAPNXMXOE-SPSCNLKESA-N Everolimus Impurity 1 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Everolimus Related Compound 3 EveroliMus-d4 Everolimus Related Compound 2 Rapamycin, 32-O-demethyl- Seco Rapamycin 28-epirapamycin Everolimus Ring-Opening Impurity 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone

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