BSJ-03-123 manufacturers
- BSJ-03-123
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- $84.00 / 1mg
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2024-11-19
- CAS:2361493-16-3
- Min. Order:
- Purity: 99.38%
- Supply Ability: 10g
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| | BSJ-03-123 Basic information |
| Product Name: | BSJ-03-123 | | Synonyms: | BSJ-03-123;Acetamide, N-[2-[2-[2-[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]ethoxy]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-;Inhibitor,CDK,PROTACs,Cyclin dependent kinase,inhibit,BSJ03123,BSJ 03 123;N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide | | CAS: | 2361493-16-3 | | MF: | C47H56N10O11 | | MW: | 937.01 | | EINECS: | | | Product Categories: | | | Mol File: | 2361493-16-3.mol |  |
| | BSJ-03-123 Chemical Properties |
| density | 1.375±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 100 mg/mL (106.72 mM; ultrasonic and adjust pH to 3 with HCl) | | pka | 10.68±0.40(Predicted) | | form | Solid | | color | White to yellow |
| | BSJ-03-123 Usage And Synthesis |
| Uses | BSJ-03-123 is a PROTAC connected by ligands for Cereblon and CDK as a potent and novel CDK6-selective small-molecule degrader. | | IC 50 | CDK6; Cereblon | | storage | Store at -20°C | | References | [1] Brand M, et al. Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML. Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9. DOI:10.1016/j.chembiol.2018.11.006 |
| | BSJ-03-123 Preparation Products And Raw materials |
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