G3-C12 TFA
中文名称 | G3-C12 TFA |
---|---|
中文同义词 | 抗肿瘤多肽H-ALA-ASN-THR-PRO-CYS-GLY-PRO-TYR-THR-HIS-ASP-CYS-PRO-VAL-LYS-ARG-OH |
英文名称 | G3-C12 TFA |
英文同义词 | G3-C12 TFA |
CAS号 | |
分子式 | C??H???N??O??S?.C?HF?O? |
分子量 | 0 |
EINECS号 | |
相关类别 | 目录多肽 |
Mol文件 | Mol File |
结构式 |
G3-C12 TFA 性质
形态 | 固体 |
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颜色 | 白色至米白色 |
序列 | H-Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg-OH |
Kd: 88 nM (Galectin-3).
G3-C12 (TFA) is a galectin-3 binding peptide, with high affinity (K d ) of 88 nM, but shows no affinity for other galectin family members or to other lectins. G3-C12 (TFA) bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%