|
|
| Product Name: | Doxorubicin-SMCC | | Synonyms: | Doxorubicin-SMCC;N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)- | | CAS: | 400647-59-8 | | MF: | C39H42N2O14 | | MW: | 762.76 | | EINECS: | | | Product Categories: | ADC LINKER | | Mol File: | 400647-59-8.mol |  |
| | Doxorubicin-SMCC Chemical Properties |
| Melting point | 162-172 °C | | Boiling point | 1022.5±65.0 °C(Predicted) | | density | 1.56±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DMF | | form | Solid | | pka | 7.35±0.60(Predicted) | | color | Orange to red |
| | Doxorubicin-SMCC Usage And Synthesis |
| Uses | Doxorubicin-SMCC is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | | In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only. | | Storage | Please store the product under the recommended conditions in the Certificate of Analysis. | | Description | N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules. |
| | Doxorubicin-SMCC Preparation Products And Raw materials |
|