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ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396 |
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sales@chem-strong.com |
| Products Intro: |
Product Name:Acalabrutinib Impurity 2
CAS:2230757-47-6
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| | Acalabrutinib Metabolite 27 Basic information |
| Product Name: | Acalabrutinib Metabolite 27 | | Synonyms: | Acalabrutinib Metabolite 27;Acalabrutinib?active?metabolite?M27;4-[8-amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-Benzamide;ACP-5862;Benzamide, 4-[8-amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-;Acalabrutinib Impurity 1;Acalabrutinib Metabolite 27 (ACP-5862);Acalabrutinib Metabolite (M27) ACP-5862 D4Q: What is
Acalabrutinib Metabolite (M27) ACP-5862 D4 Q: What is the CAS Number of
Acalabrutinib Metabolite (M27) ACP-5862 D4 | | CAS: | 2230757-47-6 | | MF: | C26H23N7O3 | | MW: | 481.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2230757-47-6.mol |  |
| | Acalabrutinib Metabolite 27 Chemical Properties |
| density | 1.34±0.1 g/cm3(Predicted) | | pka | 11.35±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | Acalabrutinib Metabolite 27 Usage And Synthesis |
| Uses | 4-[8-Amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-benzamide is a metabolite of Acalabrutinib (A115605) which is an experimental anti-cancer drug and a selective Bruton''s tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL). |
| | Acalabrutinib Metabolite 27 Preparation Products And Raw materials |
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