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ChemStrong Scientific Co.,Ltd
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Products Intro: |
Product Name:Acalabrutinib Impurity 2 CAS:2230757-47-6 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Acalabrutinib Metabolite 27 Basic information |
Product Name: | Acalabrutinib Metabolite 27 | Synonyms: | Acalabrutinib Metabolite 27;Acalabrutinib?active?metabolite?M27;4-[8-amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-Benzamide;ACP-5862;Benzamide, 4-[8-amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-;Acalabrutinib Impurity 1;Acalabrutinib Metabolite 27 (ACP-5862);Acalabrutinib Metabolite (M27) ACP-5862 D4Q: What is
Acalabrutinib Metabolite (M27) ACP-5862 D4 Q: What is the CAS Number of
Acalabrutinib Metabolite (M27) ACP-5862 D4 | CAS: | 2230757-47-6 | MF: | C26H23N7O3 | MW: | 481.51 | EINECS: | | Product Categories: | | Mol File: | 2230757-47-6.mol | ![Acalabrutinib Metabolite 27 Structure](CAS/20200611/GIF/2230757-47-6.gif) |
| Acalabrutinib Metabolite 27 Chemical Properties |
density | 1.34±0.1 g/cm3(Predicted) | pka | 11.35±0.70(Predicted) | form | Solid | color | White to off-white |
| Acalabrutinib Metabolite 27 Usage And Synthesis |
Uses | 4-[8-Amino-3-[1-oxo-4-[(1-oxo-2-butyn-1-yl)amino]butyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinyl-benzamide is a metabolite of Acalabrutinib (A115605) which is an experimental anti-cancer drug and a selective Bruton''s tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL). |
| Acalabrutinib Metabolite 27 Preparation Products And Raw materials |
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