C3a (70-77) TFA
| 中文名称 | C3a (70-77) TFA |
|---|---|
| 中文同义词 | |
| 英文名称 | C3a (70-77) TFA |
| 英文同义词 | C3a (70-77) TFA |
| CAS号 | |
| 分子式 | C??H??F?N??O?? |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
C3a (70-77) TFA 性质
| 形态 | 固体 |
|---|---|
| 颜色 | 白色至米白色 |
C3a (70-77) TFA (Complement 3a (70-77) TFA) 是对应于 C3a 的 COOH 末端的八肽，表现出 C3a 的特异性和 1 至 2％ 的生物活性。
The direct interaction of C3a(70-77) with human mononuclear leukocytes in culture results in a concentration-dependent inhibition of the generation of LIF evoked by mitogens and by the antigen SK-SD.
C3a (70-77) induces histamine release and degranulation of rat mast cells, promotes contraction of guinea pig ileal tissue, and enhances vascular permeability in human skin. C3a (70-77) selectively desensitizes ileal smooth muscle to C3a but not to human C5a, a related anaphylatoxin. The cross-desensitization indicates a specific interaction of C3a (70-77) with cellular C3a binding sites.