Company Name: |
Borenpharm Co., Ltd
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Tel: |
027-65563561 |
Email: |
sales@borenpharm.com |
Products Intro: |
Product Name:Biotin-PEG3-SH Purity:95% HPLC Package:1g; 5g Remarks:1.8g
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Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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Tel: |
15076683720 |
Email: |
klq@cw-bio.com |
Products Intro: |
Product Name:Biotin-PEG3-SH CAS:1244028-52-1 Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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Company Name: |
Shaanxi borno biotechnology co., LTD
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Tel: |
+86-13759708231 |
Email: |
asherw9@hotmail.com |
Products Intro: |
Product Name:Biotin-PEG3-SH CAS:1244028-52-1 Purity:99% HPLC Package:可分装
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| Biotin-PEG3-SH Basic information |
Product Name: | Biotin-PEG3-SH | Synonyms: | Biotin-PEG3-SH;1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[2-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]ethyl]-2-oxo-, (3aS,4S,6aR)- | CAS: | 1244028-52-1 | MF: | C18H33N3O5S2 | MW: | 435.6 | EINECS: | | Product Categories: | | Mol File: | 1244028-52-1.mol | |
| Biotin-PEG3-SH Chemical Properties |
Boiling point | 716.4±60.0 °C(Predicted) | density | 1.179±0.06 g/cm3(Predicted) | pka | 9?+-.0.10(Predicted) | form | Solid | color | White to off-white |
| Biotin-PEG3-SH Usage And Synthesis |
Biological Activity | Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Biotin-PEG3-SH Preparation Products And Raw materials |
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