| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-TOMM20 antibody produced in mouse
Purity:clone 4F3, purified immunoglobulin, buffered aqueous solutio Package:100UG Remarks:WH0009804M1-100UG
|
| Company Name: |
Riedel-de Haen AG
|
| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Remarks:clone 4F3, purified immunoglobulin, buffered aqueous solution
|
| Company Name: |
BD Biosciences
|
| Tel: |
1 877 232 8995 U.S. orders |
| Email: |
|
| Products Intro: |
|
|
| | ANTI-TOM20 Basic information |
| Product Name: | ANTI-TOM20 | | Synonyms: | ANTI-TOM20;Anti-KIAA0016;Anti-MAS20;Anti-MGC117367;Anti-MOM19;Anti-translocase of outer mitochondrial membrane 20 homolog (yeast);Monoclonal Anti-TOMM20 antibody produced in mouse | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-TOM20 Structure]() |
| | ANTI-TOM20 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-TOM20 Usage And Synthesis |
| General Description | Translocase of outer mitochondrial membrane 20 (TOMM20) is a 20kb gene with five exons and four introns, and is mapped to human chromosome 1q42.3. This gene codes for a TOMM20 receptor, which is a subunit of the outer mitochondrial membrane translocase. TOMM20 receptor contains a membrane anchor domain and a cytosolic domain, and is predominantly expressed in human cochlea. | | Biochem/physiol Actions | Translocase of outer mitochondrial membrane 20 (TOMM20) is a subunit of multiple component- dynamic complex, which plays a vital role in importing certain cytosolic proteins into or through the outer membrane of the mitochondria. It acts as a receptor for precursor proteins containing N-terminal cleavable presequences targeted to the mitochondria. Nuclear respiratory factor 2(NRF-2) plays an essential role in regulating transcription of the human TOMM20 gene. TOMM20 has potential as a prognostic biomarker and therapeutic target for gastric cancer. TOMM20 serve as a marker for mitochondrial protein import in inner ear, and reduced expression of TOMM20 is associated with Meniere′s disease. |
| | ANTI-TOM20 Preparation Products And Raw materials |
|