Company Name: |
Sigma-Aldrich
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Tel: |
021-61415566 800-8193336 |
Email: |
orderCN@merckgroup.com |
Products Intro: |
Product Name:Monoclonal Anti-TOMM20 antibody produced in mouse Purity:clone 4F3, purified immunoglobulin, buffered aqueous solutio Package:100UG Remarks:WH0009804M1-100UG
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Company Name: |
Riedel-de Haen AG
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Tel: |
800 558-9160 |
Email: |
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Products Intro: |
Remarks:clone 4F3, purified immunoglobulin, buffered aqueous solution
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Company Name: |
BD Biosciences
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Tel: |
1 877 232 8995 U.S. orders |
Email: |
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Products Intro: |
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| ANTI-TOM20 Basic information |
Product Name: | ANTI-TOM20 | Synonyms: | ANTI-TOM20;Anti-KIAA0016;Anti-MAS20;Anti-MGC117367;Anti-MOM19;Anti-translocase of outer mitochondrial membrane 20 homolog (yeast);Monoclonal Anti-TOMM20 antibody produced in mouse | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | ![ANTI-TOM20 Structure]() |
| ANTI-TOM20 Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
| ANTI-TOM20 Usage And Synthesis |
General Description | Translocase of outer mitochondrial membrane 20 (TOMM20) is a 20kb gene with five exons and four introns, and is mapped to human chromosome 1q42.3. This gene codes for a TOMM20 receptor, which is a subunit of the outer mitochondrial membrane translocase. TOMM20 receptor contains a membrane anchor domain and a cytosolic domain, and is predominantly expressed in human cochlea. | Biochem/physiol Actions | Translocase of outer mitochondrial membrane 20 (TOMM20) is a subunit of multiple component- dynamic complex, which plays a vital role in importing certain cytosolic proteins into or through the outer membrane of the mitochondria. It acts as a receptor for precursor proteins containing N-terminal cleavable presequences targeted to the mitochondria. Nuclear respiratory factor 2(NRF-2) plays an essential role in regulating transcription of the human TOMM20 gene. TOMM20 has potential as a prognostic biomarker and therapeutic target for gastric cancer. TOMM20 serve as a marker for mitochondrial protein import in inner ear, and reduced expression of TOMM20 is associated with Meniere′s disease. |
| ANTI-TOM20 Preparation Products And Raw materials |
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