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| | 2-[(4-NITROPHENYL)AMINO]ETHANOL Basic information |
| | 2-[(4-NITROPHENYL)AMINO]ETHANOL Chemical Properties |
| Melting point | 111-111.5 °C | | Boiling point | 389.5±22.0 °C(Predicted) | | density | 1.352±0.06 g/cm3(Predicted) | | form | solid | | pka | 14.57±0.10(Predicted) | | color | Yellow |
| | 2-[(4-NITROPHENYL)AMINO]ETHANOL Usage And Synthesis |
| Uses | 2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines. | | Synthesis Reference(s) | Synthesis, p. 606, 1976 DOI: 10.1055/s-1976-24135 |
| | 2-[(4-NITROPHENYL)AMINO]ETHANOL Preparation Products And Raw materials |
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