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| heparinase I Basic information |
Product Name: | heparinase I | Synonyms: | HEPARIN LYASE I;HEPARINASE;HEPARINASE I;EC 4.2.2.7;Neutralase;Lyase, heparin;Heparin lyaseI, Heparinase;HeparinaseI from Flavobacterium heparinum,Heparin lyaseI, Heparinase | CAS: | 9025-39-2 | MF: | NULL | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| heparinase I Chemical Properties |
| heparinase I Usage And Synthesis |
Uses | Heparinase I from Flavobacterium heparinum has been used:
- in the digestion of plasma samples
- to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
- in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells
| Biochem/physiol Actions | Heparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes. |
| heparinase I Preparation Products And Raw materials |
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