| Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
|
| Tel: |
+86-156-80926068 +86-15680926068 |
| Email: |
1924344760@qq.com |
| Products Intro: |
Product Name:Boc-NH-PEG1-C2-Boc
CAS:145119-18-2
Purity:98% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
|
| Company Name: |
Shanghai Aizikang Pharmaceutical Research Co., Ltd
|
| Tel: |
18721109360 |
| Email: |
306685371@qq.com |
| Products Intro: |
Product Name:tert-butyl 3-(2-(tert-butoxycarbonyl)ethoxy)propanoate
CAS:145119-18-2
Purity:97% Package:0.1g ;0.5g; 1g; 5g; 10g; 100g; 1kg
|
| Company Name: |
Combi-Blocks Inc.
|
| Tel: |
858 635 8950 |
| Email: |
sales@combi-blocks.com |
| Products Intro: |
Product Name:t-Butyl 3-(2-N-Boc-aminoethoxy)propanoate
CAS:145119-18-2
|
Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester manufacturers
- Boc-NH-PEG1-C2-Boc
-
- $0.00 / 1g
-
2024-03-25
- CAS:145119-18-2
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
|
| | Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Basic information |
| | Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Chemical Properties |
| Boiling point | 384.2±22.0 °C(Predicted) | | density | 1.026±0.06 g/cm3(Predicted) | | pka | 12.22±0.46(Predicted) |
| | Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Usage And Synthesis |
| Biological Activity | N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-,1,1-dimethylethyl ester Preparation Products And Raw materials |
|