coformycin
| 中文名称 | coformycin |
|---|---|
| 中文同义词 | 助间型霉素;化合物 T23905 |
| 英文名称 | coformycin |
| 英文同义词 | (r)-3,4,7,8-tetrahydro-3-beta-d-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-o;5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-d-ribofuranosyl-imidazo((;coformycin;(8R)-3,4,7,8-Tetrahydro-3-β-D-ribofuranosylimidazo[4,5-d][1,3]diazepin-8-ol;(8R)-3-β-D-Ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol;Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-β-D-ribofuranosyl-, (8R)-;NSC 277817 |
| CAS号 | 11033-22-0 |
| 分子式 | C11H16N4O5 |
| 分子量 | 284.27 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 11033-22-0.mol |
| 结构式 |  |
coformycin 性质
Coformycin 是一种核苷类抗生素，是腺苷脱氨酶 (adenosine deaminase , ADA) 的抑制剂。Coformycin 具有抗肿瘤和抗菌活性。
Coformycin (0.2 mg/kg, ip daily) inhibits adenosine deaminase activity for various tissues, including brain, heart, kidney, liver, etc.
| Animal Model: | Swiss-Webster mice. |
| Dosage: | 0.2 mg/kg. |
| Administration: | IP daily. |
| Result: | Inhibited adenosine deaminase activity for various tissues. |