| Company Name: |
Chengdu Kamel Pharmaceutical Co., Ltd
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| Tel: |
028-67136579 15828051124 |
| Email: |
sales@kamelpharm.com |
| Products Intro: |
Product Name:4-(3-hydroxy-butoxy)-2-butanol
CAS:821-33-0
Purity:95% Package:1g;10g;100g Remarks:002417
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| Company Name: |
JinJin Le Chemical Co., Ltd
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| Tel: |
10106090 |
| Email: |
jjlchem2@163.com |
| Products Intro: |
CAS:821-33-0
Purity:On Request Package:电询
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| | 4,4'-oxybisbutan-2-ol Basic information |
| Product Name: | 4,4'-oxybisbutan-2-ol | | Synonyms: | 4,4'-oxybisbutan-2-ol;4,4'-oxydi-2-butanol;Dibutyl 3,3''-dihydroxy ether;3,3-Dihydroxydibutyl ether;4,4'-Oxybis(2-butanol);Colenormol;Dis-Cinil;Diskin | | CAS: | 821-33-0 | | MF: | C8H18O3 | | MW: | 162.23 | | EINECS: | 212-475-3 | | Product Categories: | API | | Mol File: | 821-33-0.mol |  |
| | 4,4'-oxybisbutan-2-ol Chemical Properties |
| Melting point | <25 °C | | Boiling point | 278.4±15.0 °C(Predicted) | | density | 0.997±0.06 g/cm3(Predicted) | | pka | 14.65±0.20(Predicted) | | EPA Substance Registry System | 2-Butanol, 4,4'-oxybis- (821-33-0) |
| | 4,4'-oxybisbutan-2-ol Usage And Synthesis |
| Originator | Dyskineacutebyl,Saunier | | Definition | ChEBI: Oxydibutanol is a secondary alcohol. | | Manufacturing Process | To a solution of 3 mols butylmagnesiumbromide in ether was added dropwise an one mol of β-cyanoethyloxide. The mixture was refluxed for 1 hour. Then after cooling to the mixture was added hydrochloric acid. An organic layer was dried under sodium sulfate and evaporated. An oil layer was distilled in vacuum. The oxo-3-butane oxide has a boiling point 123-125°C at 15 mm.
A mixture of 100 g of oxo-3-butane oxide, 500 ml ethanol and 15 g Nickel Reney was loaded in autoclave and heated at 45-50°C. In autoclave was introduced a hydrogene. After cooling the mixture was filtered and ethanol was distilled off. 1,1'-Dimethyl-3,3'-oxydipropanol was distilled at 160161°C/18 mm. | | Therapeutic Function | Choleretic, Spasmolytic |
| | 4,4'-oxybisbutan-2-ol Preparation Products And Raw materials |
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