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Phygene Gold
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18059081430 |
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Product Name:GLP-1(7-37) Acetate CAS:1450806-98-0 Purity:95%-99% Package:1mg;10mg;50mg;100mg;1g;100g;1kg
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Company Name: |
Creative Peptides
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Tel: |
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Email: |
info@creative-peptides.com |
Products Intro: |
Product Name:GLP-1 (7-37) Acetate CAS:1450806-98-0 Purity:>98% Package:1g; 10g;100g;1kg Remarks:Glucagons and Glucagon-Like Peptides (GLP-1 / GLP-2)
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GLP-1(7-37)Acetate manufacturers
- GLP-1(7-37)Acetate
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- $10.00 / 1kg
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2024-07-02
- CAS:1450806-98-0
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 100 tons
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| GLP-1(7-37)Acetate Basic information |
Product Name: | GLP-1(7-37)Acetate | Synonyms: | GLP-1(7-37)Acetate;GLP-1(7-37) acetate(106612-94-6 free base);Inhibitor,inhibit,GCGR,Glucagon Receptor,GLP1(737) acetate(106612946 free base),GLP 1(7 37) acetate(106612 94 6 free base) | CAS: | 1450806-98-0 | MF: | C153H232N40O49 | MW: | 3415.77 | EINECS: | | Product Categories: | | Mol File: | 1450806-98-0.mol | |
| GLP-1(7-37)Acetate Chemical Properties |
storage temp. | Store at -20°C | solubility | Soluble in DMSO | form | Solid | color | White to off-white |
| GLP-1(7-37)Acetate Usage And Synthesis |
Description | GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion[1].
GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats[2].Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM[2]. Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with glucose IV at a variablerate for 7 hours to maintain plasma glucose concentration at 11 mM[2]. | References | [1]. Sarrauste de Menthiere, C. et al. Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production. European journal of medicinal chemistry 39, 473-480, doi:10.1016/j.ejmech.2004.02.002 (2004).
[2]. Hargrove DM, et al. Glucose-dependent action of glucagon-like peptide-1 (7-37) in vivo during short- or long-term administration. Metabolism. 1995 Sep;44(9):1231-7. |
| GLP-1(7-37)Acetate Preparation Products And Raw materials |
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