Company Name: |
Xi'an Confluore Biological Technology Co., Ltd.
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Tel: |
+86-156-80926068 +86-15680926068 |
Email: |
1924344760@qq.com |
Products Intro: |
Product Name:3,4-Dibromo-Mal-PEG2-Amine TFA salt CAS:2296708-07-9 Purity:99% HPLC Package:10MG;25MG;50MG;100MG;1G;5G Remarks:For customers outside China,please use the website:www.confluore.com
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3,4-Dibromo-Mal-PEG2-Amine TFA salt manufacturers
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| 3,4-Dibromo-Mal-PEG2-Amine TFA salt Basic information |
| 3,4-Dibromo-Mal-PEG2-Amine TFA salt Chemical Properties |
solubility | DMSO : 100 mg/mL (199.98 mM; Need ultrasonic) | form | Solid | color | White to off-white |
| 3,4-Dibromo-Mal-PEG2-Amine TFA salt Usage And Synthesis |
Biological Activity | 3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
| 3,4-Dibromo-Mal-PEG2-Amine TFA salt Preparation Products And Raw materials |
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