| Company Name: |
InvivoChem
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| Tel: |
13549236410 |
| Email: |
sales@invivochem.cn |
| Products Intro: |
Product Name:Fenebrutinib (GDC-0853) HCl
CAS:2128304-54-9
Purity:98% HPLC Package:1mg Remarks:V4148
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Fenebrutinib HCl
CAS:2128304-54-9
Purity:0 Package:25mg/RMB 10600
|
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| | Fenebrutinib (GDC-0853) HCl Basic information |
| | Fenebrutinib (GDC-0853) HCl Chemical Properties |
| | Fenebrutinib (GDC-0853) HCl Usage And Synthesis |
| Description | Fenebrutinib, also known as GDC-0853, is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, which leads to the inhibition of the growth of malignant B-cells that overexpress BTK. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B-lymphocyte development, activation, signaling, proliferation and survival. |
| | Fenebrutinib (GDC-0853) HCl Preparation Products And Raw materials |
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