| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Nitric Oxide Synthase, Inducible from mouse
Purity:recombinant, expressed in E. coli, buffered aqueous solution Package:50UN Remarks:N2783-50UN
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| Company Name: |
Shanghai Universal Biotech Co.,Ltd
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| Tel: |
13774214275 |
| Email: |
zhouzz@univ-bio.com |
| Products Intro: |
Product Name:iNOS (mouse, recombinant)
Package:250units Remarks: 见优宁维官网
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| Company Name: |
ChemeGen 中国
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| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
| Products Intro: |
Product Name:iNOS (mouse, recombinant)
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Product Name: | INOS | | Synonyms: | EC 1.14.13.39;INDUCIBLE NITRIC OXIDE SYNTHASE (MURINE RECOMBINANT);INDUCIBLE NITRIC OXIDE SYNTHASE (MURINE MACROPHAGE);INDUCIBLE NITRIC OXIDE SYNTHASE;INDUCIBLE NITRIC OXIDE SYNTHASE MOUSE;INOS;INOS, MOUSE MACROPHAGE;INOS, MOUSE, RECOMBINANT | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![INOS Structure]() |
| storage temp. | −70°C | | form | buffered aqueous solution |
| Uses | Nitric Oxide Synthase, Inducible from mouse has been used in immunohistochemical studies. It is also used to evaluate the therapeutic efficacy of inducible nitric oxide synthase (NOS) on reperfusion-induced microcirculatory alterations and hemodynamic adverse effects in the microvasculature of skeletal muscle.
| | General Description | Inducible nitric oxide synthase (iNOS), also known as inflammatory nitric oxide synthase, is a calcium independent isoenzyme, involved in synthesis of nitric oxide (NO). It is a soluble enzyme encoded by the gene mapped to mouse chromosome 11. iNOS is active in dimeric form and its activity is induced by cytokines and various other stimuli. iNOS is expressed in various inflammatory conditions. | | Biochem/physiol Actions | Tumor-derived inducible nitric oxide synthase (iNOS) plays a vital role in stimulating tumor growth and vessel maturation. Therefore, it is considered to be a potential therapeutic target for anti-vascular cancer therapies. Unchecked activity of iNOS leads to overproduction of nitric oxide (NO), which is toxic for living cells. iNOS activity can be controlled at both transcription and translational level by regulating protein stability, dimerization, phosphorylation, cofactor binding and availability of oxygen and L-arginine as substrates. iNOS plays a vital role in excisional wound repair and exhibits gene therapy strategy to advance wound healing process in iNOS-deficient conditions such as diabetes and steroid treatment. |
| | INOS Preparation Products And Raw materials |
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