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| | Malabaricone C Basic information |
| Product Name: | Malabaricone C | | Synonyms: | Malabaricone C;1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one;1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone;1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-;lipid metabolism,Inhibitor,sphingomyelin synthase,SMS 1,diet,obesity,inhibit,Malabaricone C,SMS 2 | | CAS: | 63335-25-1 | | MF: | C21H26O5 | | MW: | 358.43 | | EINECS: | | | Product Categories: | | | Mol File: | 63335-25-1.mol |  |
| | Malabaricone C Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml | | form | A crystalline solid | | color | White to off-white |
| | Malabaricone C Usage And Synthesis |
| Description | Malabaricone C is a diarylnonanoid that has been found in Myristica and has diverse biological activities. It scavenges 59.9% of 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals when used at a concentration of 7 μg/ml. Malabaricone C is active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml). It is cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively). Malabaricone C inhibits sphingomyelin synthase 1 (SMS1) and SMS2 activity in cell lysates (IC50s = 3 and 1.5 μM, respectively). It decreases body weight gain, hepatic steatosis, and hepatic and plasma triglyceride levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 0.1% in the diet. | | Uses | Malabaricone C is a useful research chemical compound from Myristica malabarica which exhibits antioxidant activity. | | Definition | ChEBI: A natural product found in Myristica cinnamomea. |
| | Malabaricone C Preparation Products And Raw materials |
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