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2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-

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2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Suppliers list
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ:65489617 15618227136
Email: info@SuperLan-chem.com
Products Intro: Product Name:BCL6-IN-6
CAS:2408882-54-0
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121 15000105423
Email: chenjw@absin.cn
Products Intro: Product Name:BCL6-IN-6
CAS:2408882-54-0
Purity:98% Package:50mg
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Email: marketing@tsbiochem.com
Products Intro: Product Name:BCL6-IN-6;BCL6 IN 6,BCL6IN6
CAS:2408882-54-0
Purity:98% Package:1 mg;10 mg;100 mg;2 mg;25 mg;5 mg;50 mg
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Email: cindy.huang@synzest.com
Products Intro: Product Name:BCL6-IN-6
CAS:2408882-54-0
Purity:98% Package:10mg 100mg
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Basic information
Product Name:2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-
Synonyms:2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-;BCL6-IN-6;BCL6 IN 6,BCL6IN6
CAS:2408882-54-0
MF:C27H31FN6O2S
MW:522.64
EINECS:
Product Categories:
Mol File:2408882-54-0.mol
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Structure
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Chemical Properties
density 1.301±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka11.58±0.70(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Usage And Synthesis
Biological ActivityBCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].
References[1]. Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63(2):676-695.
2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel- Preparation Products And Raw materials
Tag:2-Thiophenecarboxamide, 5-(1-cyclopenten-1-yl)-N-[4-[[2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5-fluoro-4-pyrimidinyl]amino]-2-methoxyphenyl]-, rel-(2408882-54-0) Related Product Information