| Company Name: |
R&D Systems, Inc
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| Tel: |
18003437475 |
| Email: |
rdname@qq.com |
| Products Intro: |
Product Name:Ac4ManNDAz
CAS:1015698-39-1
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| | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate Basic information |
| Product Name: | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate | | Synonyms: | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate;Ac4ManNDAz | | CAS: | 1015698-39-1 | | MF: | C19H27N3O10 | | MW: | 457.43 | | EINECS: | | | Product Categories: | | | Mol File: | 1015698-39-1.mol | ![D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate Structure](CAS/20210305/GIF/1015698-39-1.gif) |
| | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate Chemical Properties |
| density | 1.45±0.1 g/cm3(Predicted) | | solubility | Ethanol:45.74(Max Conc. mg/mL);100.0(Max Conc. mM)
DMSO:45.74(Max Conc. mg/mL);100.0(Max Conc. mM) | | pka | 12.89±0.70(Predicted) |
| | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate Usage And Synthesis |
| Description | Ac4ManNDAz is a cell-permeable photo-crosslinking probe for studying glycoprotein or glycolipid interactions. The compound is an unnatural diazirine-containing monosaccharide building block, which acts as a photo-crosslinker. Once inside the cell, Ac4ManNDAz is metabolized and incorporated as photo-crosslinking sialic acid analogs into cell surface glycoproteins. Upon photoactivation with UV irradiation, the sialic acid appended diazirine is activated to a reactive carbene that covalently crosslinks to nearby molecules. | | storage | Store at -20°C |
| | D-Mannopyranose, 2-deoxy-2-[[3-(3-methyl-3H-diazirin-3-yl)-1-oxopropyl]amino]-, 1,3,4,6-tetraacetate Preparation Products And Raw materials |
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