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| | Ethyl 7-chloro-2-oxoheptanoate Basic information |
| Product Name: | Ethyl 7-chloro-2-oxoheptanoate | | Synonyms: | Ethyl 7-chloro-2-oxohepanoate;ETHYL 7-CHLORO-2-OXOHEPTANOATE;Ethyl 7-Chloro-2-Otoheptanoate;ALPHA KETO ESTER (ETHYL 7-CHLORO-2-OXOHEPTANOATE);Heptanoic acid,7-chloro-2-oxo-, ethyl ester;ICK, active, GST tagged human;MGC46090;Ethyl -7-chloro-2-oxo heptonate | | CAS: | 78834-75-0 | | MF: | C9H15ClO3 | | MW: | 206.67 | | EINECS: | 278-992-1 | | Product Categories: | API;bc0001 | | Mol File: | 78834-75-0.mol |  |
| | Ethyl 7-chloro-2-oxoheptanoate Chemical Properties |
| Boiling point | 281.2±23.0 °C(Predicted) | | density | 1.093±0.06 g/cm3(Predicted) | | refractive index | 1.4510 to 1.4560 | | storage temp. | Inert atmosphere,2-8°C | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear Yellow | | CAS DataBase Reference | 78834-75-0(CAS DataBase Reference) |
| | Ethyl 7-chloro-2-oxoheptanoate Usage And Synthesis |
| Chemical Properties | Colorless to Light orange to Yellow clear liquid. | | Uses | Ethyl 7-chloro-2-oxoheptanoate is a product of the Grignard reaction that can be used to synthesize organic compounds. It has been used in the preparation of pharmaceuticals such as cilastatin, which is used to inhibit cytochrome P450 enzymes in order to prolong the effectiveness of other drugs. This reagent also reacts with hydrochloric acid to form ethyl chloride and heptanoic acid, which can be used for chlorination reactions. | | Uses | Ethyl 7-Chloro-2-oxoheptanoate is a reagent used in the synthesis of selective BCL-XL inhibitor A1155463 used in the treatment of cancer. | | Preparation | Ethyl 7-chloro-2-oxoheptanoate is an organochlorine compound that is obtained by reacting ethyl chloride with magnesium in the presence of benzene and cilastatin as a catalyst. |
| | Ethyl 7-chloro-2-oxoheptanoate Preparation Products And Raw materials |
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