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Shanghai Chaolan Chemical Technology Center
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Product Name:4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone
CAS:886599-05-9
Purity:98% Package:50MG;100MG,1G,5G,100G
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| | 4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Basic information |
| | 4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Chemical Properties |
| Boiling point | 616.4±55.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | pka | 6.00±0.70(Predicted) |
| | 4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Usage And Synthesis |
| Uses | GW814408X is a kinase chemical genome group (KCGS) compound that inhibits the AURKC kinase involved in cell cycle progression, checkpoint regulation, and cell division. GW814408X exhibits cell line-dependent toxicity, e.g., cytotoxic effects on HeLa cells. GW814408X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1]. | | References | [1] Wells CI, et al. The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification. Int J Mol Sci. 2021 Jan 8;22(2):566. DOI:10.3390/ijms22020566
[2] Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8(3):e57888. DOI:10.1371/journal.pone.0057888 |
| | 4-Pyridinecarboxaldehyde, 2-[7-(3-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yl]hydrazone Preparation Products And Raw materials |
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