ENZYME FO
中文名称 | ENZYME FO |
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中文同义词 | ENZYME FO |
英文名称 | factor 420 |
英文同义词 | factor 420;7,8-didemethyl-8-hydroxy-5-deazariboflavin;Coenzyme FO;enzyme FO |
CAS号 | 37333-48-5 |
分子式 | C16H17N3O7 |
分子量 | 363.32208 |
EINECS号 | |
相关类别 | |
Mol文件 | 37333-48-5.mol |
结构式 | ![]() |
ENZYME FO 性质
储存条件 | Store at -20°C |
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溶解度 | 二甲基亚砜:5 mg/mL(13.76 mM) |
形态 | 固体 |
颜色 | 黄至棕色 |
The formation of Coenzyme FO is mediated by two separate radical SAM active sites, one each in the CofG and CofH enzymes or both in the FbiC enzyme. These two radical SAM domains constitute the functional domains of Fo synthase. F420 is biosynthesized in
Methanocaldococcus jannaschii
by the action of eight enzymes with the formation of the deazaflavin chromophore (Fo) as the remaining unsolved step.
Coenzyme F420 is the central low-redox-potential electron carrier in methanogenic metabolism. Coenzyme F420 is reduced under hydrogen by the action of F420-dependent hydrogenase.
Coenzyme F420 acts as a hydride transfer coenzyme for an F420-specific glucose-6-phosphate dehydrogenase (Fgd) in
mycobacteria
. Coenzyme F420 is found in all methanogenic and certain nonmethanogenic archaea, where it participates in energy metabolism, NADP reduction, oxygen detoxification, and sulfite reduction. By converting NO2 back to NO with F420H2,
M. tuberculosis
could decrease the effectiveness of antibacterial action of macrophages.
安全信息
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/04/30 | HY-136497 | ENZYME FO Coenzyme FO | 37333-48-5 | 5mg | 4500元 |
2024/04/30 | HY-136497 | ENZYME FO Coenzyme FO | 37333-48-5 | 10mg | 7500元 |