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| 2-amino-4-phosphonobutyric acid Basic information |
| 2-amino-4-phosphonobutyric acid Chemical Properties |
Melting point | 229-231 °C(Solv: ethanol (64-17-5); water (7732-18-5)) | Boiling point | 491.7±55.0 °C(Predicted) | density | 1.628±0.06 g/cm3(Predicted) | storage temp. | Store at RT | solubility | Water:9.15(Max Conc. mg/mL);50.0(Max Conc. mM) | form | White solid. | pka | 2.19±0.10(Predicted) | Water Solubility | Soluble to 50 mM in water |
| 2-amino-4-phosphonobutyric acid Usage And Synthesis |
Description | DL-AP4 is a broad-spectrum glutamatergic antagonist. DL-AP4 (2.5 mM) inhibits electrically stimulated synaptic transmission in rabbit hippocampal slices. It also depresses depolarizations induced by NMDA , L-homocysteate, or kainate in isolated frog spinal cord when used at a concentration of 1 mM. DL-AP4 (0.2 mM) inhibits the accumulation of inositol induced by ibotenate , quisqualate, L-glutamate, and L-aspartate in rat hippocampal slices. | Uses | DL-2-Amino-4-phosphonobutanoic acid (AP4) is an amino-acid derivative reported to block cone signals in the rat retina. Improves learning and memory processes in passive and active avoidance situations in rats. | storage | Store at RT |
| 2-amino-4-phosphonobutyric acid Preparation Products And Raw materials |
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