| Company Name: |
Shanghai Chaolan Chemical Technology Center
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| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:Pan- RAS-IN-2
CAS:3034673-92-9
Purity:98% Package:50MG;100MG,1G,5G,100G
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| | Pan-RAS-IN-2 Basic information |
| | Pan-RAS-IN-2 Chemical Properties |
| form | Solid | | color | White to light yellow |
| | Pan-RAS-IN-2 Usage And Synthesis |
| Uses | Pan-rasin-2 (compound 6A) is a molecular glues that targets RAS. Pan-rasin-2 has significant inhibitory activity on cell proliferation of RAS mutant cell lines. Pan-rasin-2 can form ternary complexes with cyclophilin A (CYPA) and RAS (ON) proteins and the formation of ternary complexes can block the binding of RAF downstream of RAS, which has anti-tumor effects[1]. | | References | [1] Y Zhang, et al. Macrocyclic derivative and use thereof. WO2024067857A1. 2023-09-28 |
| | Pan-RAS-IN-2 Preparation Products And Raw materials |
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