| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
info@efebio.com |
| Products Intro: |
Product Name:Taurohyocholic Acid (sodium salt)
CAS:117997-17-8
Purity:95% Package:5mg;10mg;25mg
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| Company Name: |
HX Pharmaceutical technology co., LTD
|
| Tel: |
15671363360 |
| Email: |
494267389@qq.com |
| Products Intro: |
Product Name:TAUROHYOCHOLATE
CAS:117997-17-8
Purity:98% HPLC Package:10mg，25mg，50mg，100mg
|
| Company Name: |
SHANGHAI ZZBIO CO., LTD.
|
| Tel: |
19921389125 19921389125 |
| Email: |
tech@zzbioco.com |
| Products Intro: |
Product Name:Taurohyocholic Acid Sodium Salt
CAS:117997-17-8
Purity:96%HPLC Package:10mg;
|
| Company Name: |
Cayman Chemical Company
|
| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Product Name:Taurohyocholic Acid (sodium salt)
CAS:117997-17-8
|
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| | TAUROHYOCHOLATE Basic information |
| Product Name: | TAUROHYOCHOLATE | | Synonyms: | TAUROHYOCHOLATE;Ethanesulfonic acid, 2-[[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt | | CAS: | 117997-17-8 | | MF: | C26H45NO7S | | MW: | 515.703 | | EINECS: | | | Product Categories: | | | Mol File: | 117997-17-8.mol |  |
| | TAUROHYOCHOLATE Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml | | form | A lyophilized powder |
| | TAUROHYOCHOLATE Usage And Synthesis |
| Biological Activity | Taurohyocholic acid (THCA) is a taurine-conjugated form of the porcine-specific primary bile acid hyocholic acid .1 THCA inhibits precipitation of cholesterol crystals by stabilizing cholesterol in the liquid-crystalline phase.2 It prevents cholestasis and cellular necrosis induced by taurolithocholic acid in isolated rat livers.3 THCA levels are increased in the urine of patients with hepatitis B-induced cirrhosis.4 | | References | 1.Wahlstr?m, A., Sayin, S.I., Marschall, H.-I., et al.Intestinal crosstalk between bile acids and microbiota and its impact on host metabolismCell Metab.24(1)41-50(2016)
2.Juste, C., Catala, I., Henry, R., et al.Influence of bile salt molecular species on cholesterol crystallization from supersaturated model bilesBiochim. Biophys. Acta.1254(1)89-97(1995)
3.Scholmerich, J., Kitamura, S., Baumgartner, U., et al.Taurohyocholate, taurocholate, and tauroursodeoxycholate but not tauroursocholate and taurodehydrocholate counteract effects of taurolithocholate in rat liverRes. Exp. Med. (Berl.)190(2)121-129(1990)
4.Wang, X., Xie, G., Zhao, A., et al.Serum bile acids are associated with pathological progression of hepatitis B-induced cirrhosisJ. Proteome Res.15(4)1126-1134(2016) |
| | TAUROHYOCHOLATE Preparation Products And Raw materials |
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