5-Chloro-2-nitrobenzenesulfonic acid

5-Chloro-2-nitrobenzenesulfonic acid Basic information
Product Name:5-Chloro-2-nitrobenzenesulfonic acid
Synonyms:5-Chloro-2-nitrobenzenesulfonic acid;2-nitro-5-chlorobenzenesulfonic acid;Benzenesulfonic acid, 5-chloro-2-nitro-
CAS:54481-12-8
MF:C6H4ClNO5S
MW:237.62
EINECS:
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Mol File:54481-12-8.mol
5-Chloro-2-nitrobenzenesulfonic acid Structure
5-Chloro-2-nitrobenzenesulfonic acid Chemical Properties
Safety Information
MSDS Information
5-Chloro-2-nitrobenzenesulfonic acid Usage And Synthesis
Physical properties5-Chloro-2-nitrobenzenesulfonic Acid, forms hygroscopic crystals of the monohydrate.
UsesReduction of 5-Chloro-2-nitrobenzenesulfonic acid gives 4-chloroaniline-2-sulfonic acid, and amination results in 4- nitroaniline-3-sulfonic acid, both of minor importance as intermediates. The derived sulfonyl chloride leads to 5-chloro-2-nitrobenzenesulfonamide, an intermediate in the production of the benzothiadiazine derivative diazoxide, used as a vasodilator.
Production Methods5,5' -Dichloro-2,2' -dinitrodiphenyldisulfide (obtained from the reaction of 2,4-dichloronitrobenzene with Na2S2) is oxidatively chlorinated with chlorine in HCl – HNO3 to give the sulfonyl chloride, which hydrolyzes to 5-Chloro-2-nitrobenzenesulfonic acid.
5-Chloro-2-nitrobenzenesulfonic acid Preparation Products And Raw materials
Raw materials2,4-Dichloronitrobenzene-->Chlorine-->disodium disulphide
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