| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-TF
Purity:Ab1, Prestige Antibody
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| | ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN Basic information |
| Product Name: | ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN | | Synonyms: | Anti-Siderophilin antibody produced in rabbit;Anti-TF antibody produced in rabbit;Anti-Transferrin antibody produced in rabbit;Anti-β-1-Metal-binding globulin antibody produced in rabbit;Anti-CD142;Anti-coagulation factor III (thromboplastin, tissue factor);Anti-TFA;ANTI-TF | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN Structure]() |
| | ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution |
| | ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN Usage And Synthesis |
| Uses | Anti-TF antibody produced in rabbit is suitable for global protein profiling to find new molecular biomarkers for common, multifactorial disorders.
Anti-TF antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | TF (transferrin) is a 80kDa monomeric blood plasma glycoprotein with iron bindinding property. It is braodly divded into two regions with two iron binding sites. Both the N-terminal and C-terminal domains consist of two sub domains (N1 and N2, C1 and C2) connected by a hinge region. | | Biochem/physiol Actions | TF (transferrin) gene encodes a glycoprotein that binds to two Fe3+ ions in association with the binding of an anion, usually bicarbonate. It functions in transporting iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. Most of the bound iron is utilized for the synthesis of hemoglobin by developing erythroid cells. It may also facilitate the removal of certain organic matter and allergens from serum by binding to granulocyte/pollen. Defects in this gene are associated with atransferrinemia, characterized by abnormal synthesis of transferrin leading to iron overload and microcytic hypochromic anemia. |
| | ANTI-HUMAN THOMSEN-FRIEDENREICH ANTIGEN Preparation Products And Raw materials |
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