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| (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Basic information |
Product Name: | (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester | Synonyms: | (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester;Vincamajine;Ajmalan-16-carboxylic acid, 19,20-didehydro-17-hydroxy-, methyl ester, (2α,17S,19E)-;O-Deacetylvincamedine | CAS: | 2506-26-5 | MF: | C22H26N2O3 | MW: | 366.46 | EINECS: | | Product Categories: | | Mol File: | 2506-26-5.mol | |
| (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Chemical Properties |
Melting point | 226.5-227°C | Boiling point | 524.1±50.0 °C(Predicted) | density | 1.36±0.1 g/cm3(Predicted) | pka | 13.63±0.40(Predicted) |
| (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Usage And Synthesis |
Description | A minor constituent of Vinca major, this alkaloid has been obtained by chromatography of the alkaloidal fraction followed by recrystallization from MeOH when it forms long, colourless needles. It is laevorotatory with [α]D - 55° (c 0.45,
96% EtOH). The crystalline hydrochloride has m.p. 259-261°C (dec.); [α]D -40° (c 0.38, H2O). One secondary non-phenolic hydroxyl group is present and the O-acetate is identical with Vincamedine (q.v.). | References | Janot, LeMen., Compt. rend., 241,767 (1955) |
| (2α,17S,19E)-19,20-Didehydro-17-hydroxyajmalan-16-carboxylic acid methyl ester Preparation Products And Raw materials |
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