| Company Name: |
Chengdu Youngshe Chemical Co., Ltd. |
| Tel: |
+8618108235634 |
| Email: |
Cecilia@youngshechem.com |
| Products Intro: |
Product Name:(Gly1,Gln416,Thr613,Tyr7,Asp10,Asn11, Pro14, Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (human, rat)
CAS:313988-89-5
Purity:0.98 Package:1G;10G
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| | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Basic information |
| Product Name: | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) | | Synonyms: | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human);(Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26,Met30,Ala31,Aib32)-Neuropeptide Y (huMan, rat);H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH2;PubChem ID: 90479787;(Gly1,Ser3middot22,Gln4middot34,Thr6,Arg19,Tyr21,Ala23middot31,Aib32)-Pancreatic Polypeptide (human);Glycyl-L-prolyl-L-seryl-L-glutaminyl-L-prolyl-L-threonyl-L-tyrosyl-L-prolylglycyl-L-α-aspartyl-L-asparaginyl-L-alanyl-L-threonyl-L-prolyl-L-α-glutamyl-L-glutaminyl-L-methionyl-L-alanyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-tyrosyl-L-isoleucyl-L-asparaginyl-L-methionyl-L-alanyl-2-methylalanyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosinamide;(Gly?,Ser?·??,Gln?·??,Thr?,Arg??,Tyr??,Ala??·??,Aib??)-Pancreatic Polypeptide (human) trifluoroacetate salt;Gly1,Gln4·16,Thr6·13,Tyr7,Asp10,Asn11,Pro14,Arg26 | | CAS: | 313988-89-5 | | MF: | C183H281N57O54S2 | | MW: | 4207.66874 | | EINECS: | | | Product Categories: | | | Mol File: | 313988-89-5.mol |  |
| | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble to 1 mg/ml in 10% acetonitrile | | form | Powder | | color | White to off-white |
| | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Usage And Synthesis |
| Biological Activity | cPP1-7,NPY19-23,Ala31,Aib32,Gln34 is a potent and selective neuropeptide YY5 receptor agonist with IC50 of 0.24 nM for hY5 receptor binding. It increases dietary intake. | | in vitro | cPP1-7,NPY19-23,Ala31,Aib32,Gln34 has IC 50 s of 530 nM, >500 nM , 51 nM for binding to the hY 1 , hY 4 , hY 2 receptors. | | in vivo | cPP1-7,NPY19-23,Ala31,Aib32,Gln34 induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g. | | target | | hY 5 receptor < /p> 0.24 nM (IC 50 ) | hY 1 receptor 530 nM (IC 50 ) | hY 2 receptor >500 nM (IC 50 ) | hY 4 receptor 51 nM (IC 50 ) | |
| | (Gly1,Ser3·22,Gln4·34,Thr6,Arg19,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) Preparation Products And Raw materials |
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