2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride

2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:R 568 hydrochloride
CAS:177172-49-5
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:Tecalcet Hydrochloride;R-568 (hydrochloride)
CAS:177172-49-5
Purity:98.00% Package:10 mg;2 mg;5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:Tecalcet hydrochloride
CAS:177172-49-5
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:Tecalcet HCl (KRN568; NPS-R568; R568)
CAS:177172-49-5
Purity:98% Package:10mg Remarks:V13565
Company Name: Aromsyn Co., Ltd.
Tel: +86-0571-85585865 +8613336024896
Email: CB@aromsyn.com
Products Intro: Product Name:(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-amine hydrochloride
CAS:177172-49-5
Purity:NLT 95% Package:1G;1KG;100KG Remarks:AS102318
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Basic information
Product Name:2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride
Synonyms:2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride;R 568 hydrochloride;Tecalcet (Hydrochloride);R-568;Tecalcet HCl (KRN568;NPS-R568;R-568 hydrochloride >=95% (HPLC);Benzenepropanamine, 2-chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-, hydrochloride (1:1)
CAS:177172-49-5
MF:C18H23Cl2NO
MW:340.28732
EINECS:
Product Categories:
Mol File:177172-49-5.mol
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Structure
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Chemical Properties
Melting point 183.3-184.4 °C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO : 50 mg/mL (146.93 mM; Need ultrasonic)
form Powder
color White to off-white
Safety Information
MSDS Information
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Usage And Synthesis
DescriptionCalcium-sensing receptor (CaSR) is a G protein-coupled receptor that is involved in calcium homeostasis. Activation of CaSR on parathyroid cells decreases the secretion of parathyroid hormone (PTH), which in turn reduces blood calcium concentration. R-568 is a calcimimetic compound that can allosterically activate or positively modulate the human CaSR. It dose-dependently decreases circulating levels of PTH in both normal individuals and patients with primary hyperparathyroidism in clinical trials. R-568 is used in research to explore novel actions of CaSR.
UsesR 568 Hydrochloride is a calcimimetic, which prevents vascular remodeling in uremia.
UsesTreatment of hyperparathyroidism and related disorders, such as hypercalcemia (reduction of PTH secretion through modulation of calcium ion receptors on parathyroid cells).
Brand nameNorcalcin (Amgen).
storageDesiccate at RT
2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride Preparation Products And Raw materials
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