(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate manufacturers
- Miriplatin hydrate
-
- $59.00 / 5mg
-
2024-11-06
- CAS:250159-48-9
- Min. Order:
- Purity: 99.6%
- Supply Ability: 10g
|
| (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Basic information |
| (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Chemical Properties |
storage temp. | Store at -20°C | solubility | 25℃: DMSO | form | Powder |
| (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Usage And Synthesis |
Biological Activity | Miriplatin hydrate (SM-11355 hydrate) is an effective chemotherapeutic agent and is a kind of alkylator. | in vitro | Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis. | in vivo | Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells. |
| (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Preparation Products And Raw materials |
|