Company Name: |
Haoyuan Chemexpress Co., Ltd.
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021-58950125 |
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Product Name:Sodium formononetin-3'-sulfonate CAS:949021-68-5 Purity:>98% Package:2558RMB/5mg
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Company Name: |
Guangzhou QiYun Biotechnology Co., Ltd.
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020-61288194 61288195 |
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505721671@qq.com |
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Product Name:Sodium formononetin-3'-sulfonate CAS:949021-68-5 Purity:98% Package:4604RMB/10mg
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Company Name: |
Musechem
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+1-800-259-7612 |
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Product Name:Sodium formononetin-3'-sulfonate CAS:949021-68-5 Purity:>98% HPLC Package:10mg;100mg;1g Remarks:Reagent Grade
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Fan De(Beijing) Biotechnology Co., Ltd.
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15911056312 |
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Product Name:SodiuM forMononetin-3-sulfonate CAS:949021-68-5 Purity:97.0% Package:5mg
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| SodiuM forMononetin-3'-sulfonate Basic information |
Product Name: | SodiuM forMononetin-3'-sulfonate | Synonyms: | SodiuM forMononetin-3'-sulfonate;5-(7-Hydroxy-4-oxo-4H-1-benzopyran-3-yl)-2-methoxybenzenesulfonic acid sodium salt (1:1);Sodium formononetin-3(acute)-sulfonate;sodium 4'-methoxy-7-hydroxyisoflavone-3'-sulfonate;Sodium formononetin-3'-sulfonate;Sodium formononetin-3'-sulfonate (Sul-F) | CAS: | 949021-68-5 | MF: | C15H9NaO7S | MW: | 356.28253 | EINECS: | | Product Categories: | | Mol File: | 949021-68-5.mol | ![SodiuM forMononetin-3'-sulfonate Structure](CAS/GIF/949021-68-5.gif) |
| SodiuM forMononetin-3'-sulfonate Chemical Properties |
storage temp. | Store at -20°C | form | Solid | color | White to off-white | Water Solubility | Water: 25 mg/mL (67.51 mM) |
| SodiuM forMononetin-3'-sulfonate Usage And Synthesis |
Description | Sodium formononetin-3'-sulfonate (Sul-F) is a water-sol. derivate of formononetin. IC50 value:Target: Research results showed that treatment with Sul-F significantly prevented the elevation of ST-segment level, decreased the contents of creatine kinase-MB, lactate dehydrogenase, alanine aminotransferase and cardiac troponin T in serum and reduced the myocardium necrosis scores. These findings indicate that Sul-F has a protective potential against myocardial infarction injury. A possible mechanism for the protective effect is the elevated expression of endogenous antioxidant defense enzymes degraded lipid peroxidn. products and improved energy metab. of cardiac mitochondrial, thus attenuating cardiocyte apoptosis. Other reaearch results showed that sodium formononetin-3'-sulfonate not only had favorable water, solubility but also had good lipid-lowering and liver-protection activities.
| References | [1]. Zhang, Shumin; Tang, Xuexi; Tian, Jingwei et al. Cardioprotective effect of sulphonated formononetin on acute myocardial infarction in rats. Basic & Clinical Pharmacology & Toxicology (2011), 108(6), 390-395.
[2]. Wang, Qiuya; Meng, Qinghua; Zhang, Zunting et al. Synthesis, solubility, lipids-lowering and liver-protection activities of sulfonated formononetin. Yaoxue Xuebao (2009), 44(4), 386-389.
[3]. Cardioprotective Effect of Sulfonated Formononetin on Acute Myocardial Infarction in Rats. |
| SodiuM forMononetin-3'-sulfonate Preparation Products And Raw materials |
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