| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:LUF6000
CAS:890087-21-5
Purity:>98% Package:3069RMB/5mg
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LUF 6000 manufacturers
- LUF6000
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- $327.00 / 5mg
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2024-10-24
- CAS:890087-21-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | LUF 6000 Basic information |
| Product Name: | LUF 6000 | | Synonyms: | LUF 6000;N-(3,4-Dichlorophenyl)-2-cyclohexyl-1H-imidazo[4,5-c]quinolin-4-amine;2-Cyclohexyl-N-(3,4-dichlorophenyl)-1H-imidazo[4,5-c]quinolin-4-amine;LUF-6000;LUF 6000;3H-Imidazo[4,5-c]quinolin-4-amine, 2-cyclohexyl-N-(3,4-dichlorophenyl)- | | CAS: | 890087-21-5 | | MF: | C22H20Cl2N4 | | MW: | 411.33 | | EINECS: | | | Product Categories: | | | Mol File: | 890087-21-5.mol |  |
| | LUF 6000 Chemical Properties |
| Melting point | 237-240℃ (methanol water ) | | Boiling point | 650.5±55.0 °C(Predicted) | | density | 1.401±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 14.29 mg/mL (34.74 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | | form | Powder | | pka | 12.13±0.40(Predicted) | | color | Light brown to brown |
| | LUF 6000 Usage And Synthesis |
| Uses | LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2]. | | in vivo | LUF6000 induces anti-inflammatory effect in 3 experimental animal models of rat adjuvant induced arthritis, monoiodoacetate induced osteoarthritis, and concanavalin A induced liver inflammation in mice[2]. | | References | [1] Du L, et al. Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. Purinergic Signal. 2018;14(1):59-71. DOI:10.1007/s11302-017-9592-1
[2] Cohen S, et al. A? adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action. Mediators Inflamm. 2014;2014:708746. DOI:10.1155/2014/708746 |
| | LUF 6000 Preparation Products And Raw materials |
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