| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:KCC2 blocker 1
CAS:1228439-36-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:KCC2 blocker 1;KCC2 blocker 1,KCC-2 blocker 1
CAS:1228439-36-8
Purity:98% Package:10 mg
|
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| | Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Basic information |
| | Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (601.68 mM) | | form | Solid | | color | Light yellow to khaki |
| | Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Usage And Synthesis |
| Biological Activity | KCC2 blocker 1 is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect[1]. | | References | [1]. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5. |
| | Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester Preparation Products And Raw materials |
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