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Product Name:(2R,3R)-2-(2,4-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol CAS:135133-23-2 Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Basic information |
Product Name: | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol | Synonyms: | (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol;(alphaR)-alpha-(2,4-Difluorophenyl)-alpha-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-1H-1,2,4-triazole-1-ethanol;Efinaconazole Impurity 39;(2R,3R)-2-(2,4-difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)oxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol(WXG00770);(2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether;1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-[(tetrahydro-2H-pyran-2-yl)oxy]ethyl]-, (αR)-;Efinaconazole Impurity F;(2R,3R)-2-(2,4-Difluorophenyl)-3-((tetrahydro-2H-pyran-2-yl)... | CAS: | 135133-23-2 | MF: | C17H21F2N3O3 | MW: | 353.36 | EINECS: | | Product Categories: | | Mol File: | 135133-23-2.mol | ![(2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Structure](CAS/20150408/GIF/135133-23-2.gif) |
| (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical Properties |
Boiling point | 533.9±60.0 °C(Predicted) | density | 1.35±0.1 g/cm3(Predicted) | pka | 11.61±0.29(Predicted) |
| (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Usage And Synthesis |
Uses | (2R,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol 3-THP Ether is an impurity of efinaconazole (E435070). |
| (2R,3R)-2-(2,4-difluorophenyl)-3-(tetrahydro-2H-pyran-2-yloxy)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Preparation Products And Raw materials |
Raw materials | 1-Propanone, 2-(acetyloxy)-1-(2,4-difluorophenyl)--->4-[(2R)-2-(3,4,5,6-tetrahydro-2H-pyran-2-yloxy)-propionyl]morpholine-->1-Propanone, 1-(2,4-difluorophenyl)-2-hydroxy-, (2R)--->2-((R)-1-((R)-2-(2,4-difluorophenyl)oxiran-2-yl)ethoxy)tetrahydro-2H-pyran-->2,4-difluoro phenyl magnesium bromide-->1,2,4-Triazole-->1,2,4-Triazolylsodium-->1-Bromo-2,4-difluorobenzene-->3,4-Dihydro-2H-pyran |
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