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MedChemexpress LLC
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Product Name:Helioxanthin 8-1
CAS:840529-13-7
Purity:>98% Package:2333RMB/2mg
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| Company Name: |
SPIRO PHARMA
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eric_feng1954@126.com |
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Product Name:Helioxanthin 8-1
CAS:840529-13-7
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
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Guangzhou QiYun Biotechnology Co., Ltd.
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020-61288194 61288195 |
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Product Name:Helioxanthin 8-1
CAS:840529-13-7
Purity:98% Package:5000RMB/10mg
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Musechem
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+1-800-259-7612 |
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info@musechem.com |
| Products Intro: |
Product Name:Helioxanthin 8-1
CAS:840529-13-7
Purity:>98% HPLC Package:10mg;100mg;1g Remarks:Reagent Grade
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| | Helioxanthin 8-1 Basic information |
| Product Name: | Helioxanthin 8-1 | | Synonyms: | Helioxanthin 8-1;11-(1,3-Benzodioxol-5-yl)-8,9-dihydro-1,3-benzodioxolo[4,5-g]phthalazine-7,10-dione;1,3-Benzodioxolo[4,5-g]phthalazine-7,10-dione, 11-(1,3-benzodioxol-5-yl)-8,9-dihydro-;Helioxanthin analogue 8-1;CS-1213;Helioxanthin 8 1,Helioxanthin 81 | | CAS: | 840529-13-7 | | MF: | C20H12N2O6 | | MW: | 376.32 | | EINECS: | | | Product Categories: | | | Mol File: | 840529-13-7.mol |  |
| | Helioxanthin 8-1 Chemical Properties |
| Melting point | 318-320 °C | | density | 1.548±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | pka | 10.56±0.20(Predicted) | | color | Light yellow to yellow |
| | Helioxanthin 8-1 Usage And Synthesis |
| Biological Activity | helioxanthin 8-1, an analogue of helioxanthin (ach126447), is an inhibitor of hbv and hiv virus with ec50 values of 0.03 μm and 2.7 μm, respectively [1].helioxanthin 8-1 is the cyclic hydrazide derivative of helioxanthin and has shown significant in vitro antivirus activity with ec50 values of 0.03 μm and 2.7 μm for hbv and hiv, respectively [1]. in the ds-tet5 cells, helioxanthin 8-1 can inhibit duck hepatitis b virus (dhbv) dna synthesis with a mean ic50 value of 0.25±0.05 μm. besides, in induced cells and non-induced ds-tet5 cells, helioxanthin 8-1 has cytotoxic effect with cc50 values of 18±2 μm and 45±3 μm, respectively, by using an mtt assay [2]. | | references | [1] yeo h1, li y, fu l, zhu jl, gullen ea, dutschman ge, lee y, chung r, huang es, austin dj, cheng yc. synthesis and antiviral activity of helioxanthin analogues. j med chem. 2005 jan 27;48(2):534-46.
[2] ying c1, tan s, cheng yc. helioxanthin analogue 8-1 inhibits duck hepatitis b virus replication in cell culture. antivir chem chemother. 2010;21(2):97-103. |
| | Helioxanthin 8-1 Preparation Products And Raw materials |
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