| Company Name: |
AdooQ BioScience, LLC
|
| Tel: |
+1 (866) 930-6790 |
| Email: |
info@adooq.com |
| Products Intro: |
Product Name:GNE-900
CAS:1200126-26-6
Purity:98% Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Email: |
eric_feng1954@126.com |
| Products Intro: |
Product Name:GNE 900
CAS:1200126-26-6
Purity:95% -98%HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG;100KG
|
| Company Name: |
Absin Bioscience Inc.
|
| Tel: |
021-38015121 15000105423 |
| Email: |
wulan@absin.cn |
| Products Intro: |
Product Name:GNE-900
CAS:1200126-26-6
Purity:>98% Package:5mg;10mg
|
|
| | GNE 900 Basic information |
| Product Name: | GNE 900 | | Synonyms: | GNE 900;PPYHOOZGDDPLKM-UHFFFAOYSA-N;GNE900; GNE 900;9H-Pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile, 3-[4-(1-piperidinylmethyl)phenyl]- | | CAS: | 1200126-26-6 | | MF: | C23H21N5 | | MW: | 367.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1200126-26-6.mol |  |
| | GNE 900 Chemical Properties |
| form | Solid | | color | Light yellow to brown |
| | GNE 900 Usage And Synthesis |
| Description | GNE-900 is an ATP-competitive, selective, and orally bioavailable ChK1 inhibitor. In combination with chemotherapeutic agents, GNE-900 sustains ATR/ATM signaling, enhances DNA damage, and induces apoptotic cell death. GNE-900 has little single-agent activity in the absence of chemotherapy and does not grossly potentiate the cytotoxicity of gemcitabine in normal bone marrow cells. In vivo scheduling studies show that optimal administration of the ChK1 inhibitor requires a defined lag between gemcitabine and GNE-900 administration. (Mol Cancer Ther; 12(10); 1968-80). |
| | GNE 900 Preparation Products And Raw materials |
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