Company Name: |
Chengdu Dianchun Technology Co., Ltd
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Tel: |
400-1166-196 18502815961 |
Email: |
cdhxsj@163.com |
Products Intro: |
Product Name:1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (ammonium salt) CAS:1246355-57-6 Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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Company Name: |
Creative Enzymes
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Tel: |
1-516-855-7709 |
Email: |
info@creative-enzymes.com |
Products Intro: |
Product Name:PI(4,5)P2 CAS:1246355-57-6
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| 1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Basic information |
| 1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Chemical Properties |
| 1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Usage And Synthesis |
Uses | TopFluor? PI(4,5)P2 or 1-oleoyl-2-{6-[4-(dipyrrometheneboron difluoride)butanoyl]amino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (ammonium salt) has been used as a fluorescent lipid in living cells to analyse the cellular localization of phosphatidylinositol (PI) and in the preparation of giant unilamellar vesicles (GUVs) for the ezrin-membrane tethering assays. | General Description | Although PI(4,5)P2 is a minor component of cell membranes, it plays a critical role as a substrate for a number of important signaling proteins. PI(4,5)P2 is an intermediate in the IP3/DAG pathway where it is hydrolyzed by phospholipase C to liberate the second messengers, inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PI(4,5)P2 is also a substrate for PI 3-kinase where it is phosphorylated to PI(3,4,5)P3, an activator of downstream signaling components such as the protein kinase AKT. |
| 1-oleoyl-2-{6-[4-(dipyrroMetheneboron difluoride)butanoyl]aMino}hexanoyl-sn-glycero-3-phosphoinositol-4,5-bisphosphate (aMMoniuM salt) Preparation Products And Raw materials |
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