- CZC-54252
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- $32.00 / 1mg
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2024-11-01
- CAS:1191911-27-9
- Min. Order:
- Purity: 99.39%
- Supply Ability: 10g
- CZC-54252
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- $1.00 / 1KG
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2024-10-22
- CAS:1191911-27-9
- Min. Order: 1KG
- Purity: MIn98%HPLC/LC
- Supply Ability: 100KGS
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| | CZC-54252 Basic information |
| Product Name: | CZC-54252 | | Synonyms: | N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide;CZC 54252 hydrochloride;CZC-54252;CS-1730;N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride;CZC 54252;CZC54252;CZC-54252, >98%;Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]- | | CAS: | 1191911-27-9 | | MF: | C22H25ClN6O4S | | MW: | 504.99 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1191911-27-9.mol |  |
| | CZC-54252 Chemical Properties |
| Boiling point | 718.1±70.0 °C(Predicted) | | density | 1.452±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 20 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 10 mg/mL | | form | Powder | | pka | 8.50±0.10(Predicted) | | color | White to off-white |
| | CZC-54252 Usage And Synthesis |
| Uses | CZC 54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations are associated with familial Parkinson''s disease and a potential therapeutic target. | | Definition | ChEBI: CZC-25146 is a member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is an aminopyrimidine, a member of morpholines, an aromatic ether, an organochlorine compound, a sulfonamide and a secondary amino compound. |
| | CZC-54252 Preparation Products And Raw materials |
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