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| ANTI-HUMAN FACTOR X Basic information |
Product Name: | ANTI-HUMAN FACTOR X | Synonyms: | ANTI-HUMAN FACTOR X;ANTI-FACTOR X;Monoclonal Anti-Factor X antibody produced in mouse | CAS: | | MF: | | MW: | 0 | EINECS: | | Product Categories: | | Mol File: | Mol File | |
| ANTI-HUMAN FACTOR X Chemical Properties |
storage temp. | -20°C | form | buffered aqueous solution |
| ANTI-HUMAN FACTOR X Usage And Synthesis |
Uses | Monoclonal Anti-Factor X antibody is suitable for western blot at 0.125-0.25 ug/mL. | General Description | Factor X is the vitamin K-dependent pro-coagulants with molecular weight of 68,000. It is synthesized in the liver and consists of a heavy chain and a light chain which are linked by a disulfide bond. The primary domain present in the light chain contains 11 γ-carboxy glutamic acid residues at the N-terminal end. The N-terminal primary domain is responsible for binding of negatively charged phospholipids. Primary domain of the heavy chain present at the C-terminal end has similar characteristics with the serine proteases. | Biochem/physiol Actions | The peptide bond cleavage in the heavy chain triggers the activity of factor X zymogen and clips off a carbohydrate rich peptide. Factor X activity can also be accelerated by a protease from Russell′s viper venom. Upon activation, it catalyzes the conversion of prothrombin to thrombin. It cleaves two peptide bonds of prothrombin by binding to the Factor Va and a phospholipid on cell surfaces in presence of calcium ions. |
| ANTI-HUMAN FACTOR X Preparation Products And Raw materials |
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