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| | troponin I type 3 (cardiac) Basic information |
| | troponin I type 3 (cardiac) Chemical Properties |
| Boiling point | 632.8±55.0 °C(Predicted) | | density | 1.49±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO : 16.67 mg/mL (39.26 mM) | | pka | -1.42±0.37(Predicted) | | form | buffered aqueous solution | | color | Off-white to gray |
| | troponin I type 3 (cardiac) Usage And Synthesis |
| General Description | Troponin I3, cardiac type (TNNI3), also known as cardiac troponin I (cTnI), is the inhibitory element of troponin. It possesses an inhibitory peptide (IP) domain and a switch peptide (SP) domain that is located N-terminal of the IP domain. The gene encoding TNNI3 is localized on human chromosome 19q13.42. | | Biochem/physiol Actions | Troponin I3, cardiac type (TNNI3) or cardiac troponin I (cTnI) modulates the diastolic function of the heart. Low expression of TNNI3 is associated with cardiac diastolic dysfunction. Elevated expression of the protein indicates cardiac injury. TNNI3 is a biomarker for myocardial infarction and mutations in the gene encoding it have been linked to hypertrophic cardiomyopathy. | | storage | Store at -20°C |
| | troponin I type 3 (cardiac) Preparation Products And Raw materials |
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