| Company Name: |
Borenpharm Co., Ltd
|
| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:MS-PEG4-THP
CAS:145927-73-7
Purity:95% HPLC Package:1g; 5g Remarks:509.5g
|
| Company Name: |
Zhengzhou Acme Chemical Co., Ltd.
|
| Tel: |
0371-0371-55629727 13323845623 |
| Email: |
2885676761@qq.com |
| Products Intro: |
CAS:145927-73-7
Purity:0.98 Package:100g;250g;500g;1kg
|
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| | Mes-PEG5- THP Basic information |
| Product Name: | Mes-PEG5- THP | | Synonyms: | Mes-PEG5- THP;Mes-PEG4- THP;MS-PEG4-THP;CAS_145927-73-7;Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 1-methanesulfonate;MSPEG4THP,MS-PEG-4-THP,PROTAC Linkers,inhibit,MS PEG4 THP,Inhibitor;2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl methanesulfonate | | CAS: | 145927-73-7 | | MF: | C14H28O8S | | MW: | 356.43 | | EINECS: | | | Product Categories: | | | Mol File: | 145927-73-7.mol |  |
| | Mes-PEG5- THP Chemical Properties |
| form | Liquid | | color | Light yellow to light brown |
| | Mes-PEG5- THP Usage And Synthesis |
| Biological Activity | MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Mes-PEG5- THP Preparation Products And Raw materials |
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