| Company Name: |
Haoyuan Chemexpress Co., Ltd.
|
| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:BET-IN-1
CAS:1422554-34-4
Purity:>98% Package:1500RMB/1mg
|
| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:BET-IN-1
CAS:1422554-34-4
Purity:>98% Package:1500RMB/1mg
|
|
| | BET-IN-1 Basic information |
| Product Name: | BET-IN-1 | | Synonyms: | BET-IN-1;BET inhibitor 1;1H-Imidazo[4,5-c]quinoline, 7-(3,5-dimethyl-4-isoxazolyl)-8-methoxy-1-[(1R)-2-methoxy-1-methylethyl]-2-(tetrahydro-2H-pyran-4-yl)-;I-BET282;I-BET282E;I BET282,IBET282,I-BET-282 | | CAS: | 1422554-34-4 | | MF: | C25H30N4O4 | | MW: | 450.53 | | EINECS: | | | Product Categories: | | | Mol File: | 1422554-34-4.mol |  |
| | BET-IN-1 Chemical Properties |
| Boiling point | 613.9±55.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 32 mg/mL (71.03 mM) | | pka | 4.95±0.30(Predicted) |
| | BET-IN-1 Usage And Synthesis |
| Description | BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1, compound example 2, has a plC50 in the range 6.0 - 7.0.IC50 value: 6.0 - 7.0 (plC50)Target: bromodomain | | References | [1]. Demont Emmanuel Hubert, et al. Preparation of 4-(8-methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole, its salts and isomers and their use as bromodomain inhibitors. From PCT Int. Appl. (201 |
| | BET-IN-1 Preparation Products And Raw materials |
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