PBD-1
PBD-1 性质
pBD-1 是一种来源于猪组织的内源性组成型表达的抗菌肽 (AMP)，尤其在猪黏膜上皮部位表达。pBD-1 具有抗菌作用，并且有助于猪黏膜和系统宿主防御。
IC50: bacterial
In a northern blot analysis, pBD-1 mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs.In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express pBD-1 are peripheral blood mononuclear cells.