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| Product Name: | AEM1 | | Synonyms: | N-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine;N-(1,3-Benzodioxol-5-ylmethyl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine;AEM1
(NRF2 inhibitor AEM1);Thieno[2,3-d]pyrimidin-4-amine, N-(1,3-benzodioxol-5-ylmethyl)-5-(4-fluorophenyl)-;AEM1 >=98% (HPLC);AEM-1,AEM1,inhibit,AEM 1,Inhibitor,Keap1-Nrf2;1-(2H-1,3-benzodioxol-5-yl)-N-[5-(4-fluorophenyl)-1H,4H-thieno[2,3-d]pyrimidin-4-ylidene]methanamine | | CAS: | 1030123-90-0 | | MF: | C20H14FN3O2S | | MW: | 379.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1030123-90-0.mol |  |
| Boiling point | 582.1±50.0 °C(Predicted) | | density | 1.457±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:4): 0.2 mg/mL; DMSO: 20 mg/mL; Ethanol: 0.25 mg/mL | | form | A crystalline solid | | pka | 5.04±0.40(Predicted) | | color | White to off-white |
| Uses | N-(1,3-Benzodioxol-5-ylmethyl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine Inhibits deregulated NRF2 transcriptional activity in cancer. |
| | AEM1 Preparation Products And Raw materials |
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