| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
CAS:388622-58-0
Purity:>=99 atom % D, >=98% (CP) Package:5MG Remarks:774898-5MG
|
| Company Name: |
Shanghai EFE Biological Technology Co., Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
info@efebio.com |
| Products Intro: |
Product Name:(3β)-7-Dehydro Cholesterol-d7 (Major)
CAS:388622-58-0
Purity:95% Package:0.5mg;1mg
|
| Company Name: |
Nanjing Haolv Biotechnology Co.,Ltd
|
| Tel: |
025-84622273 17361806303 |
| Email: |
3004208264@qq.com |
| Products Intro: |
Product Name:7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
CAS:388622-58-0
Purity:98% Package:5g;25g;100g Remarks:Steroids
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:7-dehydro Cholesterol-d7
CAS:388622-58-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
|
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Basic information |
| Product Name: | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 | | Synonyms: | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;(3β)-7-Dehydro Cholesterol-d7
(See also D229462);(3β)-7-Dehydro Cholesterol-d7 (Major);Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;7-dehydro Cholesterol-d7;(32)-7-Dehydro Cholesterol-d7 (Major);Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7);2H7]-7-Dehydrocholesterol | | CAS: | 388622-58-0 | | MF: | C27H44O | | MW: | 384.65 | | EINECS: | | | Product Categories: | | | Mol File: | 388622-58-0.mol |  |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemical Properties |
| storage temp. | -70°C | | solubility | Soluble in methanol(warmed), slightly soluble in chloroform | | form | solid | | Stability: | Light Sensitive |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Usage And Synthesis |
| Uses | 7-dehydrocholesterol-d7 has been used:
- as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis
- in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis
- to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis
| | General Description | 7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol. | | Biochem/physiol Actions | 7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS). |
| | 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Preparation Products And Raw materials |
|